Research Articles
The Design-Build-Test-Learn (DBTL) Cycle in Metabolic Engineering: A Framework for Accelerating Strain Development
This article provides a comprehensive overview of the Design-Build-Test-Learn (DBTL) cycle, a foundational and iterative framework in modern metabolic engineering.
Strategic Host Chassis Selection for Advanced Metabolic Engineering: From Foundational Principles to Next-Generation Platforms
Selecting an optimal microbial chassis is a critical, multi-faceted decision that determines the success of metabolic engineering projects aimed at biomanufacturing high-value therapeutics and chemicals.
Metabolic Engineering for Advanced Biofuels: Pathway Optimization, Novel Hosts, and Industrial Scale-Up
This article synthesizes current advancements and methodologies in applying metabolic engineering to biofuel production, tailored for researchers and scientists in biotechnology and drug development.
Engineering Secondary Metabolites in Plants and Microbes: Pathways, CRISPR, and Microbial Synthesis for Drug Discovery
This article provides a comprehensive overview of modern strategies for engineering the production of valuable secondary metabolites in plants and microbes.
Genome-Scale Metabolic Modeling: A Systems Biology Framework for Drug Discovery and Biomedical Innovation
This article provides a comprehensive introduction to Genome-Scale Metabolic Models (GEMs), computational tools that define gene-protein-reaction relationships for an organism's entire metabolic network.
Flux Balance Analysis for Strain Design: A Comprehensive Guide for Biomedical Researchers
This article provides a comprehensive guide to Flux Balance Analysis (FBA) and its critical role in metabolic engineering and strain design for biomedical applications.
Advanced Metabolic Engineering Strategies for Developing Microbial Cell Factories
This article provides a comprehensive overview of contemporary metabolic engineering strategies for developing efficient microbial cell factories, targeting researchers and scientists in drug development and industrial biotechnology.
Systems Metabolic Engineering: Principles, Applications, and Future Directions for Biomedical Innovation
This article provides a comprehensive overview of systems metabolic engineering, an interdisciplinary field that integrates systems biology, synthetic biology, and evolutionary engineering to optimize metabolic networks in cells.
Engineering Xylose Metabolic Pathways in Rhodotorula toruloides for Sustainable Biomanufacturing
Discover how scientists are engineering Rhodotorula toruloides to efficiently convert xylose into valuable bioproducts, advancing sustainable biomanufacturing.
Unlocking Yeast's Palette: Engineering Nature's Vibrant Colors
Discover how scientists are using metabolomics and gene-editing technologies to engineer yeasts into efficient carotenoid production factories.